Drug Metabolism – Phase-1 and Phase-2

Drug metabolism The chemical alternation of a drug by the body is termed as drug metabolism, also known as bio transformation. The conversion of drug from one chemical form to another. The main work of drug metabolism is converting liquid soluble (non-polar) drug to water soluble (polar) drug to avoid reabsorption in renal tubules and … Read more

Medicinal chemistry and its History – mimprovement

Medicinal chemistry and its History Definition of medicinal chemistry It is the branch of chemistry, that is intersection of organic chemistry, pharmacology and various other biological specialties. It is a discipline that enclose the design, development and synthesis of pharmaceutical drugs. It also involves the studying and existing drug in their biological activity (properties) and … Read more

Nomenclature of optical isomers: D&L system and R&S system, with best notes(1)

Nomenclature of optical isomers 1. D&L system of nomenclature of optical isomers The definition of R&S configuration is more precise & quiet different D&L configuration. The D&L nomenclature was done in old system. The original system of nomenclature was started with the enantiomers of a standard compound glyceraldehyde one enantiomers rotate the plane of polarized … Read more