Drug Metabolism – Phase-1 and Phase-2

Drug metabolism The chemical alternation of a drug by the body is termed as drug metabolism, also known as bio transformation. The conversion of drug from one chemical form to another. The main work of drug metabolism is converting liquid soluble (non-polar) drug to water soluble (polar) drug to avoid reabsorption in renal tubules and … Read more

Physicochemical properties in relation to biological action – mimprovement

Physicochemical properties in relation to biological action Physicochemical properties play an important role in determining the biological action of a substance. The way a substance interacts with its environment is determined by its physicochemical properties, such as solubility, surface area, and charge. These properties can affect the absorption, distribution, metabolism and excretion of a drug … Read more

Medicinal chemistry and its History – mimprovement

Medicinal chemistry and its History Definition of medicinal chemistry It is the branch of chemistry, that is intersection of organic chemistry, pharmacology and various other biological specialties. It is a discipline that enclose the design, development and synthesis of pharmaceutical drugs. It also involves the studying and existing drug in their biological activity (properties) and … Read more